Diana Wouters Selected Research

Autoimmune Hemolytic Anemia (Cold Agglutinin Disease)

7/2023	C1-inhibitor treatment in patients with severe complement-mediated autoimmune hemolytic anemia.
1/2023	The contribution of the alternative pathway in complement activation on cell surfaces depends on the strength of classical pathway initiation.
11/2015	Lyse or not to lyse: Clinical significance of red blood cell autoantibodies.
11/2015	Complement deposition in autoimmune hemolytic anemia is a footprint for difficult-to-detect IgM autoantibodies.
11/2015	Complement inhibitors to treat IgM-mediated autoimmune hemolysis.
1/2014	Methods for quantitative detection of antibody-induced complement activation on red blood cells.
2/2013	C1-esterase inhibitor concentrate rescues erythrocytes from complement-mediated destruction in autoimmune hemolytic anemia.

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Diana Wouters Research Topics

Disease

9	Rheumatoid Arthritis 01/2016 - 03/2005
8	Inflammation (Inflammations) 01/2021 - 11/2008
7	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 07/2023 - 02/2013
6	Atypical Hemolytic Uremic Syndrome 09/2022 - 01/2018
5	Infections 01/2022 - 08/2011
4	Myocarditis (Carditis) 01/2017 - 12/2014
4	Myocardial Infarction 01/2017 - 08/2008
4	Sepsis (Septicemia) 08/2015 - 08/2008
3	Hereditary Angioedemas 01/2021 - 08/2008
3	Hemolysis 01/2020 - 01/2014
3	Autoimmune Diseases (Autoimmune Disease) 01/2017 - 11/2015
2	Meningococcal Infections 01/2022 - 01/2022
2	Wounds and Injuries (Trauma) 01/2021 - 07/2012
2	Burns 01/2021 - 07/2012
2	Necrosis 01/2021 - 01/2013
2	Lung Injury 12/2020 - 12/2016
2	Pneumonia (Pneumonitis) 01/2017 - 12/2016
2	Asthma (Bronchial Asthma) 01/2017 - 12/2015
2	Virus Diseases (Viral Diseases) 01/2017 - 08/2016
2	Neoplasms (Cancer) 01/2017 - 01/2016
2	Hemolytic Anemia 11/2015 - 11/2015
2	Malaria 08/2015 - 08/2015
2	HIV Infections (HIV Infection) 08/2015 - 08/2015
1	Thrombotic Microangiopathies 09/2022
1	Renal Insufficiency (Renal Failure) 01/2022
1	Hemolytic-Uremic Syndrome 01/2022
1	Critical Illness (Critically Ill) 12/2020
1	Ventilator-Induced Lung Injury 12/2020
1	Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis) 12/2019
1	Bacterial Meningitis 12/2019
1	Hematologic Diseases (Blood Diseases) 01/2019
1	Falciparum Malaria (Plasmodium falciparum Malaria) 07/2018
1	Parasitemia 07/2018
1	Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria) 01/2018
1	Central Nervous System Lupus Vasculitis 01/2017
1	Central Serous Chorioretinopathy 01/2017
1	Macular Degeneration (Age-Related Maculopathy) 01/2017
1	Pericarditis 08/2016
1	Heart Diseases (Heart Disease) 03/2016
1	Polymyalgia Rheumatica (Rhizomelic Pseudopolyarthritis) 01/2016
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2016
1	Acute-Phase Reaction 01/2016
1	Febrile Neutropenia 01/2016
1	Medulloblastoma 01/2016
1	Leukemia 01/2016
1	Rhabdomyosarcoma 01/2016
1	Osteosarcoma (Osteogenic Sarcoma) 01/2016
1	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 01/2016
1	Angioedema 11/2015
1	Acquired angioedema 11/2015
1	Mannose-Binding Protein Deficiency 08/2015
1	Stroke (Strokes) 02/2015
1	Jaundice (Icterus) 01/2015

Drug/Important Bio-Agent (IBA)

26	Complement System Proteins (Complement)IBA 07/2023 - 08/2011
9	AutoantibodiesIBA 07/2023 - 01/2014
9	AntibodiesIBA 01/2017 - 10/2010
7	Complement Factor H (Factor H)IBA 01/2022 - 01/2018
6	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2011
5	Adalimumab (Humira)FDA Link 10/2013 - 10/2010
4	Complement C1 Inhibitor Protein (C1 Esterase Inhibitor)IBA 01/2021 - 07/2012
4	Immunoglobulin G (IgG)IBA 01/2017 - 10/2013
2	Complement Inactivating AgentsIBA 01/2021 - 11/2015
2	Biomarkers (Surrogate Marker)IBA 07/2018 - 04/2013
2	AntigensIBA 01/2017 - 01/2014
2	Colchicine FDA LinkGeneric 01/2017 - 08/2016
2	Immunoglobulin M (IgM)IBA 11/2015 - 11/2015
2	Nucleosomes (Nucleosome)IBA 08/2015 - 01/2015
2	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 08/2015 - 08/2011
2	Peptide Hydrolases (Proteases)FDA Link 02/2015 - 05/2014
2	CytokinesIBA 01/2015 - 04/2013
2	LectinsIBA 01/2015 - 08/2011
2	Complement Receptors (Complement Receptor)IBA 01/2014 - 10/2013
2	C-Reactive ProteinIBA 04/2013 - 07/2012
1	SolventsIBA 09/2022
1	eculizumab FDA Link 09/2022
1	Detergents (Detergent)IBA 09/2022
1	Blood Proteins (Serum Proteins)IBA 01/2021
1	Complement C4 (Complement Component 4)IBA 01/2021
1	Complement C3 (C3 Complement)IBA 01/2020
1	compstatinIBA 01/2020
1	Lactic Acid (Lactate)FDA LinkGeneric 07/2018
1	Polysaccharides (Glycans)IBA 01/2017
1	KininsIBA 01/2017
1	Intravenous Immunoglobulins (IVIG)FDA Link 01/2017
1	N(6)-carboxymethyllysine (carboxymethyllysine)IBA 12/2016
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 12/2016
1	CatecholaminesIBA 03/2016
1	drotrecogin alfa activated (Xigris)FDA Link 12/2015
1	Protein CIBA 12/2015
1	AnticoagulantsIBA 12/2015
1	SerpinsIBA 11/2015
1	lipoprotein-associated coagulation inhibitor (TFPI)IBA 02/2015

Therapy/Procedure

8	Therapeutics 09/2022 - 08/2008
1	Plasma Exchange 09/2022
1	Mechanical Ventilators (Ventilator) 12/2020
1	Artificial Respiration (Mechanical Ventilation) 12/2020
1	Aftercare (After-Treatment) 01/2016
1	Drug Therapy (Chemotherapy) 01/2016
1	Erythrocyte Transfusion 11/2015
1	Organ Transplantation 02/2015